While Belgium is more or less accepting of same-sex sexuality, cases of discrimination on the basis of sexual orientation have been documented. Young people still encounter difficulties when coming out. They show higher rates of suicide ideation and attempts than do their heterosexual counterparts. Nonetheless, the situation of gays and lesbians has improved substantially in the past couple of years, thereby potentially opening up opportunities for enhanced prevention programs for gay men with HIV infection. This chapter focuses on gay life in Belgium. In a study conducted by the authors in Belgium, older gay men are more convinced than younger gay men that engaging in sex currently is less safe when compared with the past. Those with a lower educational level were more likely to be optimistic about new HIV treatments. Overall, it was learned that about three out of five gay men were generally practicing safer sex.