The independence of Panama from Colombia and the construction of the Panama Canal created countless transatlantic movements of goods, peoples, information, and ideas, including a vibrant anarchist movement in the early twentieth century. Cuba played an important role in this network, as did Spain, and, in its efforts to contain working-class radicalism in the zone that it controlled, the United States. This chapter examines the influence not just of anarcho-communists, syndicalists, and individualists, but also of “anarcho-naturists” who advocated vegetarianism, alternative lifestyles, and resistance to urban capitalist development. Racial ideology, anti-clericalism, and the incidence of the Mexican Revolution are some of the topics covered, as well as the role of individual leaders in dividing and undermining the movement on the eve of the First World War.