Jump to ContentJump to Main Navigation
LeprosyPast and Present$
Users without a subscription are not able to see the full content.

Charlotte A. Roberts

Print publication date: 2020

Print ISBN-13: 9781683401841

Published to Florida Scholarship Online: May 2021

DOI: 10.5744/florida/9781683401841.001.0001

Show Summary Details
Page of

PRINTED FROM FLORIDA SCHOLARSHIP ONLINE (www.florida.universitypressscholarship.com). (c) Copyright University Press of Florida, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in FLASO for personal use.date: 25 September 2021

The Biology of Leprosy Bacteria and How they are Transmitted to Humans

The Biology of Leprosy Bacteria and How they are Transmitted to Humans

(p.20) 1 The Biology of Leprosy Bacteria and How they are Transmitted to Humans

Charlotte A. Roberts

University Press of Florida

This chapter considers the nature of the bacterial causes of leprosy, Mycobacterium leprae and Mycobacterium lepromatosis, including research on their genomes. Paucibacillary leprosy is the high-resistance form of leprosy and multibacillary leprosy is the low-resistance form. It is clear that genomic research, including the documentation of different strains of the bacterium and identifying susceptibility and resistance genes, is providing knowledge that is helping to track transmission and identify areas within regions of countries that remain challenges for management. While it is concluded that leprosy is transmitted through the exhalation and then inhalation of bacteria-laden droplets (droplet infection), other reported mechanisms have been discussed, and there are environmental sources of the bacteria. Leprosy in children is rare, and males are affected more than females. The wide range of intrinsic (e.g., age, sex) and extrinsic (e.g., diet, living conditions) factors that make people more or less susceptible to leprosy provide a complex picture to manage when thinking about why any particular person contracts the infection. The wild nine-banded armadillo and the red squirrel natural endemic hosts for M. leprae, but while non-human primates may be affected there is no evidence of them being infected in the wild.

Keywords:   Mycobacterium leprae, Mycobacterium lepromatosis, leprosy, nine-banded armadillo, red squirrel

Florida Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .